The toolbox of an oncologists who is faced with treating liver cancer, is still limited. Fortunately, a new tool will be added shortly to target advanced unresectable liver tumours: microscopic beads loaded with the radioactive isotope holmium-166. These so-called microspheres are brought onto the market by Quirem Medical (Deventer, the Netherlands) as QuiremSpheres®. Recently, QuiremSpheres® was named a top 5 Dutch medical technology innovation [1].