Maintaining a controlled environment within the bioreactor is an essential step toward achieving optimal cell growth. Two critical factors that govern cell culture yield are the levels of dissolved oxygen (DO) in the bioreactor and the pH of the fermentation broth. The cells within the bioreactor survive only if certain process parameters, such as DO and pH, stay within specified operating conditions. To maintain these optimal process conditions, bioreactors rely on mass flow controllers to deliver accurate and stable flow of critical gases that stabilize key functions within the bioreactor. Read more
